Anti Cardiolipin antibody test for Antiphospholipid Syndrome /abnormal bloodclot
What is Anticardiolipin?
Cardiolipin is a phospholipid, or a kind of fat in the blood. The levels of these antibodies are often high in people with abnormal blood clotting, autoimmune diseases like lupus, or repeated miscarriages.
Anticardiolipin Antibodies (ACA), IgG, IgM, IgA Blood Test
The Anticardiolipin Antibodies Test, aids in the diagnosis of antiphospholipid syndrome (APS). APS is an autoimmune disorder that produces anticardiolipin antibodies. These antibodies interfere with the blood clotting process, which can result in inappropriate or excessive clotting. The presence of anticardiolipin antibodies increases a person’s risk of developing recurrent blood clots in the veins and arteries, with complications ranging from mild to life-threatening. APS is also associated with thrombocytopenia (low blood platelet count) and pregnancy-related conditions such as preeclampsia, premature labor and recurrent miscarriages.
Antiphospholipid syndrome (APS)
Antiphospholipid syndrome (APS), sometimes known as Hughes syndrome, is a disorder of the immune system that causes an increased risk of blood clots. This means people with APS are at greater risk of developing conditions such as:
#deep vein thrombosis (DVT), a blood clot that usually develops in the leg
#arterial thrombosis (a clot in an artery), which can cause a stroke or heart attack
#blood clots in the brain, leading to problems with balance, mobility, vision, speech and memory
APS doesn't always cause noticeable problems, but some people have general symptoms that can be similar to those of multiple sclerosis (a common condition affecting the central nervous system)
What causes antiphospholipid syndrome?
APS is an autoimmune condition. This means the immune system, which usually protects the body from infection and illness, attacks healthy tissue by mistake.
In APS, the immune system produces abnormal antibodies and target proteins attached to fat molecules (phospholipids), which makes the blood more likely to clot. It's not known what causes the immune system to produce abnormal antibodies. As with other autoimmune conditions, genetic, hormonal and environmental factors are thought to play a part.
Why do I need this test?
cardiolipin antibodies test may be ordered if patient often have abnormal blood clotting or abnormal bleeding. Also people with some autoimmune diseases such as lupus, have cardiolipin antibodies in their blood. When high levels of cardiolipins are found in people with antiphospholipid (anticardiolipin) syndrome (APS)
What do my test results mean?
If you're positive, you might have antiphospholipid (anticardiolipin) syndrome (APS). You will probably be retested to see if the antibody stays in your blood.
1. Take out the kit and put it at room temperature for 20-30min;
2. Dispense 1 drop of wash buffer to the test window,waiting for the liquid to wet the membrane well;
3. Add 150ul of serum (4 drops if with a sample pipet) into the test window,waiting for the liquid to be absorbed completely;
4. Add 3 drops of colloidal Gold Conjugate into the test window,waiting for the liquid to be absorbed enough;
5. Add 3 drops of wash buffer into the test window,and interpret the result within 3 minutes immediately after the liquid is absorbed adequately.
Note1: This is SERUM / plasma TEST only,
You need to be able to separate SERUM / plasma from blood, to perform this test.